Current Openings

1-20 of 30 results
Sort By

- Philadelphia, PA

Reporting to the Head of Pharmacovigilance, the Pharmacovigilance (“PV”) Lead- SDEAs manages Safety Data Exchange Agreements (SDEA)/Pharmacovigilance Agreements (PVA) for contractual relationships with license business partners and acts as a key contact person for internal and external stakeholders, managing the relationship directly throughout the lifecycle of the agreement (creation/negotiation, implementation and maintenance) including compliance oversight. The PV Lead- SDEAs will....

- Philadelphia, PA

This position within the Translational department consists of two major roles. First, the successful candidate will be required to interact with contract research organizations (CROs) and external collaborators in order to coordinate the planning, design, and execution of the in-life portion of a variety of in vivo studies. Second, the successful candidate will support the research teams performaning assays on the bench. The main responsibilities of this position include but are not limited to

- Philadelphia, PA

The Corporate Development Lead will support the identification and evaluation of new business opportunities and enabling technologies in gene therapy and related areas. The individual will oversee and lead corporate development activities including product and IP licensing, strategic collaborations, asset out-licensing, and provide overall corporate perspectives to other business relationships (e.g. supply agreements, assay development agreements, material transfer agreements). The person in....


The Research Scientist is a member of the Liver Therapeutic Area within the Translational Research Department. S/he will be responsible for:Design and construction of optimized gene expression cassettes to drive therapeutic transgene expression derived from liver cells.Experimental design, execution and data analysis for liver-directed research programs.Write study reports, manuscripts and present results at appropriate scientific meetings.Initiate and oversee joint programs with internal and....


As a senior member of the Clinical Research and Development Team, the Clinical Operations Lead - Hematology is responsible for the overall management of the clinical programs for all Hematology projects, including the implementation, execution and completion of all departmental clinical trials and site selection and management. S/he will also assist (as needed) in development of new programs and departmental initiatives and participate in strategic planning activities throughout the....

- London, United Kingdom

The Senior EU Regulatory Affairs Associate, under general guidance, prepares, reviews and submits high quality, regulatory submissions to the EMA and other health authorities within company timelines and in accordance with current regulatory guidelines and applicable legislation. Submissions include (but are not limited to) clinical trial applications, amendments, annual reports, DSURs and additional documents as needed. The Senior EU Regulatory Affairs Associate will be responsible for....


As a member of the Clinical Operations Team, the Clinical Project Manager/Senior Clinical Project Manager designs, plans, implements and executes the overall direction of clinical projects from protocol development, selection and qualification of vendors/investigational sites, operationalization of study activities (startup through closeout) and finalization of clinical study reports. S/he will collaborate with cross functional teams to design and develop clinical study protocols, develop and....


The Senior Clinical Contracts Specialist is responsible for providing support to the clinical operations group by leading the approval process for various clinical trial documents across all studies. S/he will lead the process of coordinating across clinical project managers and members of the legal team to facilitate timely approval of documents. *This position offers a flexible onsite schedule RESPONSIBILITIES:Work across all studies and therapeutic areas to support clinical study teams.In....

- Philadelphia, PA

As part of a fully integrated HR team, accountable for talent development as well as functioning as a Lead HR Business Partner providing both strategic expertise and operational execution support to a designated functional area(s). RESPONSIBILITIES: 60% Talent Development ResponsibilitiesLeads culture programs and solutions in alignment with Spark mission, vision and values including but not limited to integrating culture into the hiring, development, recognition and performance management....

- Philadelphia, PA

The QC Raw Materials Associate will be responsible for executing activities required for the cGMP compliant program (in compliance with USP/PhEur/JP) for sampling and testing of raw materials and components used in the manufacture of biological DS & DP for clinical phase and commercial gene therapy products at Spark Therapeutics’ site in Philadelphia, PA. This role will encompass the execution of RM management and testing, assisting in the implementation raw material-management software,....


The Government Payer Lead, Gene Therapy (Remote) is responsible for an assigned mix of government payers which includes Fee for Service State Medicaid (FFS Medicaid) and Medicare Administrative Carriers (MAC) Jurisdictions. The Government Payer Lead, Gene Therapy leads all Spark Therapeutics execution of key business strategies in assigned government payers. The objective of these business strategies is to advance access for patients with Rare Diseases who would benefit from Spark....


The purpose of the Patient Access Liaison-Central Zone (remote) is to be the patient facing expert on the rare/orphan/RPE65 patient journey and the liaison for all Spark team members involved in the process. The incumbent is responsible for engaging and identifying key stakeholders on next steps to support appropriate patients accessing therapy. Work closely with the internal case management team, zone leadership, zone team and managed markets payer leads. Key logistical activities will....


The Senior Research Contracts Specialist is responsible for providing expert and timely support for the development, execution and maintenance of agreements related to preclinical and clinical research conducted by or on behalf of Spark Therapeutics. The role will work closely with the preclinical, clinical, medical and legal departments to support the preparation, review, negotiation and administration of contracts to ensure that the interests of the company are anticipated and protected....

- Philadelphia, PA

The Medical Information Associate is responsible for creating and providing timely, accurate and balanced medical/scientific and technical information (e.g., standard response documents, scientific slide decks, clinical dossiers) for employee and Medical Information Call Center use to respond to medical questions; document and respond to medical inquiries as required; create positive customer interactions; capture potential adverse events; and provide disease state, product, and Medical....

- Philadelphia, PA

The Drug Product Manufacturing Lead will oversee and manage the external drug product manufacturing vendors and sites (CMOs) providing final formulation, aseptic filling and packaging/labeling services for drug product intended for commercial and/or clinical distribution. The incumbent will lead cross-functional programs to ensure a consistent approach across drug product manufacturing sites through formalized technology transfer procedures, standardized comparability and process validation....


With a reporting line to the CFO, provides general administrative support to department senior leadership and other department members in a fast-paced environment. Primary responsibility is to ensure the needs of employees in the department are prioritized, organized and executed to maximize productivity. Daily general administrative items include calendar management, scheduling of meetings, phone and email support, departmental expense report management and company-wide (World Travel) expense

- Philadelphia, PA

This role is a critical member of the Global Medical Affairs team. The ideal candidate will be responsible for development and implementation of high-impact strategic publications, physician-directed communications, medical education, and medical advocacy plans for company products. The ideal candidate will have significant leadership experience in the pharmaceutical industry, experience with scientific publications, and the ability to develop collaborative relationships with colleagues, key....

- London, United Kingdom

The Medical Affairs Lead – EU Hematology reports into our Medical Strategy Lead – Hematology, based in Philly.. You would be responsible for leading development and execution of EU-focused medical strategy and tactics, including disease state awareness activities, clinical data presentations, KOL engagement, market access support, and patient identification in support of Spark’s hemophilia program. You'll lead hematology-related medical support for the Regulatory and Clinical Development....


The purpose of the Patient Access Liaison- Southern Territory (Remote) is to be the patient facing expert on the rare/orphan/RPE65 patient journey. The incumbent is responsible for engaging and identifying key stakeholders on next steps to support appropriate patients accessing therapy. Work closely with the internal case management team, zone leadership, zone team and managed markets payer leads. Key logistical activities will include touch points with Treatment Centers, patients, market....


The Medical Science Liaison (MSL) will be responsible for providing non-promotional scientific, educational, and research support for Spark Therapeutic gene therapy portfolio in the respective territory. The MSL position is a field based member of the Medical Affairs team. The MSL should be highly trained in a health care field and well versed in clinical practice and basic science. The MSL should be able to deliver cutting edge data and technical/practical education to Health Care....

1-20 of 30 results