Current Openings

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- Philadelphia, PA

The Supply Chain Lead is relied upon to maintain a holistic understanding of the demand and supply dynamics affecting Spark’s US product portfolio. This strategic role combines aspects of product strategy, procurement, supply chain planning and logistics for clinical and commercial supply of novel gene therapies. The Supply Chain Lead is responsible for supporting launch and post launch product strategy delivery for the US Market. S/he will drive and execute supply chain and operations....


The Facilities Maintenance & Metrology Lead will establish operational objectives and assignments to ensure effective management of maintenance and metrology programs for Spark’s growing multi-site cGMP and Scientific facilities infrastructure. This individual will be tasked with overseeing the maintenance, calibration, operation and continuous improvement of all cGMP and scientific facilities process and support equipment, utilities, and analytical equipment. Through effective and....


The Sr. Quality Control Microbiologist will support method transfer, method qualification, method suitability testing, validation and routine testing of microbiological assays. This role will coordinate the development and implementation of new programs that govern general and microbiology specific laboratory practices, lead OOS and Alert / Action Investigations, generate deviation documentation and trend reports, and assist with audit preparation and participation. He or she will create,....

- Philadelphia, PA

The Technical Operations CMC Project Management Lead is responsible for leading cross-functional teams within Technical Operations on multiple projects from inception through completion, coordinating activities to develop the physical product, manufacturing process, supply chain and regulatory files for successful launch and ongoing commercial supply. In this role, the incumbent will build, grow, and mature the CMC function within Technical Operations. This individual must possess strong....

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