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This position is a key participant in the day-to-day operation and planning of rAAV vector production related work, with primary responsibility to execute established protocols of manufacturing research and pre-clinical grade rAAV vectors. The individual in the role will participate in (but not be limited to) manufacturing of rAAV vectors including cell culture, vector production and purification, and rAAV related assays. Additionally, the individual will contribute to the implementation of....


The Upstream Process Development Scientist is involved in the development, scale-up, optimization, technology transfer, characterization and validation of recombinant adeno-associated viral vector (rAAV) production processes. The Upstream Process Development Scientist executes experiments, develops production procedures and other relevant documentation, and works under supervision. Job responsibilities are as follows:Plans procedural and experimental approaches to meet Process Development....


The Process Development Lab Associate will be primarily responsible for daily operations of the development labs and enabling the advancement of project work. Reporting to the Project & Lab Manager, the incumbent will work closely with development scientists, including upstream, downstream, analytical, and formulation functions to drive projects to key milestones. This role will also collaborate with Pre-Clinical Operations (PCO) to ensure timely delivery of raw material supply to various....


This role is a critical member of the Process Development Leadership team. The PD Downstream & Assay Leader will direct, lead and manage the development of industry scale downstream purification processes for Spark’s purification platforms. This includes, but is not limited to, all the serotypes of recombinant adeno-associated viral vectors (rAAV) from bench research to full scale cGMP manufacture. She/he is responsible for the successful transfer of the developed downstream process to....


The Process Development Scientist-Purification is key team member in the development of Spark’s fully scalable purification processes of recombinant adeno-associated viral vectors (rAAV). She/he will actively participate in the process validation (PV) project. The major responsibilities are, but not limited, to following: Work with other PD scientist team members to develop fully scalable purification process of rAAV vectors.Design and conduct experiments to optimize purification conditions to

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