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- Philadelphia, PA
new job!

The Research Associate - Liver will:With guidance and supervision from the group leader or supervisor, participate in design and execution of bioanalytical assays such as immunoassays, cell-based and molecular biology-based assays.Implement new assays and optimize existing assays based on in-depth knowledge of basic laboratory techniques.Participate in sample management activities such as receiving, processing, storage and shipping clinical and preclinical samples.Work with senior staff to....

- Philadelphia, PA
new job!

The Research Associate - Discovery will:With guidance and supervision from the group leader or supervisor, participate in design and execution of high-level molecular biology and protein based assays.Implement new assays or optimize existing assays based on in-depth knowledge of basic laboratory techniques.Participate in sample management activities such as receiving, processing, storage and shipping clinical and preclinical samples.Work with senior staff to ensure the availability of adequate

- Philadelphia, PA
new job!

- Facilitate financial close procedures including preparing general journal entries, account reconciliations, and search for accruals; - Assist with fixed asset accounting - Complete monthly bank reconciliations - Assist in documentation, testing and monitoring of internal controls for Sarbanes Oxley compliance; - Assist with International ledgers and intercompany transactions. - Perform other related duties and assist with special projects as assigned. RESPONSIBILITIES: 60% Prepare and record

- Philadelphia, PA

The New Product Planning Lead will be responsible for bringing customer insights and market knowledge to shape the profile for commercial success of Sparks gene therapy pipeline assets and inform decision making. The individual will also lead cross-functional target organ and disease area strategic initiatives and perform commercial assessments of external Business Development opportunities. The New Product Planning Lead will be a member of the Candidate Development & Program Teams and....


The Regulatory Operations Specialist contributes to daily operations activities for preparation of regulatory submissions and collaborates with interdisciplinary teams and Regulatory Affairs staff in the management of submission components and tracking of deliverables. S/he is responsible for various aspects of publishing submissions and/or submission components. This includes operational tasks associated with or in support of authoring (formatting, editing, reviewing), publishing, and....

- London, United Kingdom

The Medical Affairs Lead – EU Hematology will report to the Medical Strategy Lead – Hematology with an indirect reporting line to the Medical Affairs Lead - EU. They are responsible for leading development and execution of EU-focused medical strategy and tactics, including disease state awareness activities, clinical data presentations, KOL engagement, market access support, and patient identification in support of Spark’s hemophilia program. They will lead hematology-related medical support....


The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. This position is home based in Denmark, Sweden or Norway. The GDL will drive genotyping diagnostic efforts through....


The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully initiate and....


The Senior Office Administrator will support Spark’s European Headquarters office by providing general administrative support to select European leaders and visitors, coordinate office logistics such as printing/copying needs, office supplies, meeting support, liaising with vendors. The incumbent must be customer oriented, flexible, a team player, and is expected to have the judgment necessary to prioritize conflicting goals, keeping everyone aware of the conflicts and communicating....

- Philadelphia, PA

This role is a critical member of the Global Medical Affairs team. The ideal candidate will be responsible for overseeing the development and implementation of high-impact strategic medical communication, education, publication and medical advocacy plans for company products. The ideal candidate will have significant leadership experience in the pharmaceutical industry, coupled with strong team management skills, and the ability to develop collaborative relationships with colleagues,....

- Philadelphia, PA

The Neuroscience Lead (or CNS) will manage the CNS functional group within the Discovery Research group under Translational Research. He/she will be responsible for: - Providing leadership within a group of scientists/research associates, to develop pre-clinical programs from early discovery to the clinic . - Initiate and oversee joint programs with academic collaborators. - Establishing project timelines and ensuring work is completed according to schedule. - Training and developing staff at....


The Ocular Pre-Clinical Research Lead will manage the Ocular functional group within the Research department. He/she will be responsible for: - Providing leadership within a group of 2 to 3 scientists/research associates, to develop pre-clinical programs from early discovery to the clinic. - Initiate and oversee joint programs with academic collaborators. - Establishing project timelines and ensuring work is completed according to schedule. - Training and developing staff at varying levels of....


Provides ongoing administrative support to multiple members of a department in a fast-paced environment. The primary accountability is to ensure the needs of the function are prioritized, organized and executed in order to maximize productivity. This is accomplished by coordinating the support of the various leaders, as well as routine departmental support as requested. Daily items for assigned personnel include calendar management, scheduling of meetings and interviews, phone support, expense

- Philadelphia, PA

The Sr Field Enablement Specialist is responsible for ensuring the effective delivery, customization and utilization of enabling technologies, including Customer Relationship Management (CRM), to field sales teams. Monitors the assigned field organization’s compliance with required standards for maintaining CRM data. The lead will ensure that our field based organization is well-equipped with the technological tools and training, targeting and execution data, and ongoing support needed to....

- Philadelphia, PA

Responsible for the development of robust pre-clinical in vitro and in vivo models to test proof of concept therapeutic molecules, design experiments in collaboration with internal stakeholders to investigate how candidate therapeutics engage the immune system, and stay current on scientific literature. RESPONSIBILITIES: 30% Perform in vitro and in vivo immunological assays to help broaden our understanding of how our therapeutic leads can affect immune system interactions 20% Collaborate with

- London, United Kingdom

Serving as both a member of the Legal Leadership team and European Regional Leadership Team, the European General Counsel will establish a collaborative and proactive partnership with regional and local management in Europe, represent regional and local requirements within the Global Legal Department. As an extension of the Global Compliance team, will serve as an advisor on compliance laws and regulations. RESPONSIBILITIES: 30% Provide ongoing legal advice to senior management on laws,....

- Philadelphia, PA

This position is responsible for providing strategic and tactical direction for statistical activities across all projects in all phases of development and ensuring that proper statistical analyses and interpretations are carried out. This position will be responsible for managing all CRO activities related to statistics, programming and data management to support all development programs. S/he will be responsible for building the biometrics function at Spark. RESPONSIBILITIES: - Responsible....


The Country Lead will report to the EU Medical Affairs Lead and be responsible for supporting country-focused medical strategy and tactics, including disease state awareness activities, clinical data presentations, KOL engagement, market access support, and patient identification. They will lead development of strong KOL relationships and be the primary point of contact for research-based opportunities, including investigator-sponsored trials, local congress activities, educational grants and....


The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully initiate and....


The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully initiate and....

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