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The Assay Development Associate - Vector Shedding/Bio Distribution will:With guidance and supervision from the group leader or supervisor, conduct clinical and preclinical sample analysis per SOPs and generate data with high scientific quality to meet GLP regulatory expectations.Participate in validation of bioanalytical assays such as immunoassays and cell-based assays.Implement new assays or optimize existing assays based on in-depth knowledge of laboratory techniques.Participate in sample....

- Philadelphia, PA
new job!

The Total Rewards Lead will provide day-to-day oversight of Spark’s compensation and benefits programs including administration, communications, and education. The Lead will provide research, analytical support and recommendations into the design and implementation of Spark’s Total Rewards programs. This role partners within HR, as well as across Finance, Legal, and various client groups, serving as a consultant and subject matter expert on compensation and benefits programs and policies.....

- Any US State
new job!

STATES COVERED: New York City, Long Island and Northern NJ The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each US Region responsible to accelerate patient identification across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned region. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully execute....

- Any US State
new job!

STATES COVERED: DC, KY, OH, MD, Western PA, WV, TN - The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each US Region responsible to accelerate patient identification across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned region. - The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully execute....

- London, United Kingdom
new job!

The EU Marketing Lead will serve as brand champion, with responsibility for developing, implementing and managing key aspects of the EU marketing strategy. He/she will lead the execution of the tactical implementation, initially supporting the potential launch of voretigene neparvovec across all customer segments and then oversee their adaption for other key EU markets. Working within the Voretigene EU Launch Team to ensure that all projects are delivered on time within budget and scope.....

- Philadelphia, PA

The primary responsibility of the Patient Access Specialist (PAS) is to serve as the initial point of contact and internal liaison for patients and families participating in Spark’s ID YOUR IRD genetic testing initiative. The incumbent will monitor the patient journey and provide feedback to cross-functional Spark internal team members involved in the process. It is critical that the PAS provide strong emotional support and empathy for the patient and caregivers, while counseling and guiding....


The IT Infrastructure & Operations Lead is responsible for the smooth operation of all Spark IT Infrastructure and Help Desk service delivery. This includes data centers, networks, help desk, telecommunications, cyber security, web services, specialized departmental applications and related technologies and services. This position requires a mix of strategic IT planning and tactical execution skills. This position requires a proven track record in data center and network operations, IT....


The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully initiate and....


The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully initiate and....

- , United Kingdom

The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully initiate and....


The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each country/cluster responsible to accelerate patient identification for RPE65 mediated LCA/RP and eventually across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned country/cluster. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully initiate and....


Be part of a small communications team with a driving ambition to break down barriers for patients and families affected by debilitating genetic diseases globally. The Internal Communications Specialist will be responsible for creating an internal communication strategy and plan, executing that plan, measuring its success, and enhancing initiatives as needed. The person will be, at different times, a writer, project manager, event manager, digital expert, critical/creative thinker,....

- London, United Kingdom

The European Patient Advocacy Lead is responsible for supporting Spark’s interactions with specific non-profit advocacy organizations in the Inherited Retinal Disease, Hemophilia, and allied Rare Diseases communities throughout Europe under the direction of the Head of Patient Advocacy. This individual will help to build an internal culture focused on understanding and incorporating patient and family perspectives into everyday decision making and work to position Spark as the advocacy leader....


The Regional Commercial Head will build and lead the Country and commercial operations for Spark Therapeutics and drive the achievement of market objectives prior to and beyond launch. This individual will have full responsibility for market entry approach and the commercial presence for Spark Therapeutics in our therapeutic areas. RESPONSIBILITIES: - Work with commercial headquarters group to ensure a timely Health Technology Assessments are completed - Partner with Global Commercial to....


Provides support to the Chief Scientific Officer in our fast-paced and growing environment. The primary accountability is to ensure the needs of the executive and their function are prioritized, organized and executed in order to maximize their productivity. Daily responsibilities include calendar management, scheduling of meetings, phone support, expense reports, travel arrangements, word processing of documents, archival of documents, development of presentation slides, tracking/processing....


This position will be responsible for the development and management of a Global Supply Chain function within the Technical Operations Organization to ensure reliable, accurate and consistent delivery of product. This function will be responsible for the strategic management of drug substance and drug product supply chain for the commercialization of Spark’s lead product as well as for our clinical product pipeline. Point of contact with clinical program management, finance and new product....


The EU Regulatory Affairs Lead will interface with EMA and other EU competent authorities for the assigned project. S/he will work independently to prepare submissions, which may include Briefing Documents for Agency meetings, clinical trial applications, Orphan Drug Applications, Pediatric Plans and Marketing Applications. S/he will contribute to shaping clinical development programs to meet the needs of EU and other ex-US regulatory stakeholders. The right candidate for this role will be a....

- Philadelphia, PA

The Office Management Lead is responsible for managing the day-to-day services and operations that support Spark’s multiple office environments. S/he will collaborate with functional managers and administrative assistants to centralize, develop, and implement scalable processes and systems that streamline office and business support operations across the organization. S/he will establish Office Management leadership through the buildup of the Office Management group, build and develop....


Under general guidance from the Analytical Development Lead, working closely with colleagues in R&D and Quality Control, the successful candidate will develop, optimize and qualify immunoassays, qPCR-based methods, chromatography and/or electrophoresis methods for use in gene therapy product characterization. S/he will provide written and oral updates to project teams and provide support for regulatory document filings. This is a hands-on laboratory based position in a fast-paced, dynamic....

- Philadelphia, PA

The QC Compliance Lead will be directly responsible for GMP compliance in quality control laboratory. Under the general guidance of the management, s/he will work independently to ensure all data integrity and GMP/GDP and regulatory requirements are met. - Develops and oversees systems and authors SOPs to manage the department metrics. - The QC Compliance Lead will hire, train and manage a small team of QC Compliance associates to meet the business needs - Responsible for developing and....

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