Current Openings

1-20 of 37 results
Sort By

- , Germany
new job!

The Country Lead will report to the EU Medical Affairs Lead and be responsible for supporting country-focused medical strategy and tactics, including disease state awareness activities, clinical data presentations, KOL engagement, market access support, and patient identification.They will lead development of strong KOL relationships and be the primary point of contact for research-based opportunities, including investigator-sponsored trials, local congress activities, educational grants and....

- , France
new job!

The Country Lead will report to the EU Medical Affairs Lead and be responsible for supporting country-focused medical strategy and tactics, including disease state awareness activities, clinical data presentations, KOL engagement, market access support, and patient identification.They will lead development of strong KOL relationships and be the primary point of contact for research-based opportunities, including investigator-sponsored trials, local congress activities, educational grants and....


The Sr COE Medical Specialist will support the in-house Medical Affairs team in the development and execution of tactical and outreach plans to future treatment centers (Centers of Excellence – COEs) related to the potential launch of the first gene therapy product for an ocular disease in the United States. She/he will be responsible for the day-to-day interaction and ongoing communication with COEs as well as vendors involved with COE post-launch activities. She/he will drive the tactical....

- Philadelphia, PA

Reporting to the Materials Management Lead, the Materials Planner will provide on-going day-to-day operations and planning support to the clinical and commercial GMP Manufacturing Operations, for all products and therapeutic areas at Spark. Responsibilities include but are not limited to: - Lead site materials plan cycle (Raw Materials/Consumables through to Bulk Drug Substance) for GMP manufacturing - Lead the MRP process including inventory projection and control, coordinate all aspects of....

- London, United Kingdom

The EU Marketing Lead will serve as brand champion, with responsibility for developing, implementing and managing key aspects of the EU marketing strategy. He/she will lead the execution of the tactical implementation, initially supporting the potential launch of voretigene neparvovec across all customer segments and then oversee their adaption for other key EU markets. Working within the Voretigene EU Launch Team to ensure that all projects are delivered on time within budget and scope.....


The Environmental, Health & Safety (EHS) Lead will be responsible for developing, implementing and managing Spark’s EHS program. S/he will be responsible for monitoring site activities and ensuring compliance with federal, state and local regulatory requirements at all Spark sites and locations globally (current and future sites). This individual will ensure EHS compliance across multiple functions, and will work closely with R&D, Finance/Procurement, Quality Assurance, Project....

- Philadelphia, PA

The Materials Management Lead will be a member of the Manufacturing leadership team and have overall responsibility for building a raw material and drug substance supply planning, materials and inventory management function for Spark’s facility at 3737 Market St and off-site Raw Materials Warehouse. This will include building and leading a team to deliver efficient systems and processes. This individual will work closely with Manufacturing Operations, Finance/Procurement, Quality Assurance,....

- Philadelphia, PA

The Sr Network Engineer provides Network engineering and Systems engineering for the IT infrastructure. This is a Sr level engineering role in IT Infrastructure team. S/he is responsible for designing overall technical architecture, making technical recommendations, implementing new projects as well as changes/upgrades to current IT infrastructure services at Spark and provides technical guidance to rest of the IT team. RESPONSIBILITIES: 50% of the timeTechnical - Manage and maintain IT....


The Assay Development Associate– Cell Based will:With guidance and supervision from the group leader or supervisor, conduct clinical and preclinical sample analysis per SOPs and generate data with high scientific quality to meet GLP regulatory expectations.Participate in validation of bioanalytical assays such as immunoassays and cell-based assays.Implement new assays or optimize existing assays based on in-depth knowledge of laboratory techniques.Participate in sample management activities....


The Assay Development Associate - Vector Shedding/Bio Distribution will:With guidance and supervision from the group leader or supervisor, conduct clinical and preclinical sample analysis per SOPs and generate data with high scientific quality to meet GLP regulatory expectations.Participate in validation of bioanalytical assays such as immunoassays and cell-based assays.Implement new assays or optimize existing assays based on in-depth knowledge of laboratory techniques.Participate in sample....


As part of an overall cross functional Software Development Lifecycle (SDLC) approach to computer systems compliance and validation, the Sr Computer Systems Validation (CSV) Specialist will be involved in all aspects of computer systems validation and qualification within a GxP regulated environment. Under the general guidance of the Computer Systems Validation Lead, the Sr CSV Specialist will be involved in the overall development and maintenance of GxP system lifecycle documentation. This....

- Philadelphia, PA

Reporting to the Head of Pharmacovigilance, the Lead Pharmacovigilance (“PV”) Scientist will collaborate closely with the Head of PV to ensure Spark protects patients’ safety by providing safety support for products in various stages of clinical development and follow them through their lifecycle and commercialization. S/he will serve as lead for PV activities aligned to the strategy, goals and objectives of the Pharmacovigilance function in compliance with requisite global and local....

- Philadelphia, PA

The Medical Information Leader is responsible for leading the creation, review, and approval of timely, accurate, and balanced medical/scientific and technical information (e.g., standard response documents, clinical dossiers) across all therapeutic areas for employee and Medical Information Call Center use when responding to unsolicited medical questions. The Medical Information Leader will also document and respond to medical inquiries as required; create positive customer interactions;....


The Process Development Project Manager will:Manage PD and PCO projects, develop timeline for PD and PCO projects and oversee progress of each project. Working together with PD members to write technical reports and coordinate technical transfers.Work closely with the Process Development scientists and PCO team to ensure timely raw material supply, implement and manage an inventory system for chemicals and biological reagents; work closely with Spark facility team and others to maintain....


The primary goals of Analytical Sciences are: to lead the phase-appropriate optimization, qualification, verification and validation of analytical methods across the product development lifecycle from clinical to commercialization; provide support to QC in the investigation of non-conformances, invalid assays; and troubleshooting method problems. Analytical sciences will also be responsible for developing and overseeing a critical reagents management program, the reference standard program,....

- Philadelphia, PA

Leads the implementation and ongoing support of an IT quality, regulatory and statutory compliance program. Responsible for managing the definition, implementation, and integration of quality processes. Ensures that quality methods and procedures are executed. Analyzes best in class processes and incorporates into processes as applicable. Responsible for researching, developing and implementing testing methods and procedures. Monitors and reports defects. Works closely with leads in internal....


Reporting to the Head of Medical Information, the Senior Administrative Assistant provides ongoing administrative support to multiple members of the medical information department in a fast-paced environment. The primary accountability is to ensure the needs of the Head of Medical Information and members of the function are prioritized, organized and executed in order to maximize productivity. This is accomplished by coordinating the support of the various team members, as well as routine....

- Philadelphia, PA

Under the general direction of the Drug Product Manufacturing and Facilities Lead, the Logistics and Supply Chain Lead will work across clinical and commercial products to ensure reliable, accurate, and consistent supply coordination and movement plans. S/he is responsible to build an efficient supply chain function to support the commercialization of SPK-RPE65. He/She will support the launch team with all supply chain related activities (lead time, batch size, supply scenarios, inventory, and

- Philadelphia, PA

The Liver Discovery Research Lead will manage the Liver functional group within the Discovery Research group under Translational Research. He/she will be responsible for: - Providing leadership within in a group of scientists/research associates, to develop pre-clinical programs from early discovery to the clinic. - Initiate and oversee joint programs with academic collaborators. - Establishing project timelines and ensuring work is completed according to schedule. - Training and developing....


STATES COVERED: CA, AZ, HI, NM, NV The Genetic Diagnostic Lead (GDL) is a field based Diagnostic Leader in each US Region responsible to accelerate patient identification across all company therapeutic areas. The core objective will be to establish deep diagnostic expertise in line with the overarching global diagnostic strategy within the assigned region. The GDL will drive genotyping diagnostic efforts through disease awareness and education to successfully execute Spark’s ID Your IRD....

1-20 of 37 results